Andrew Huberman explains the neuroscience of fear, trauma, and post-traumatic stress, detailing the brain and body circuits that generate and maintain these states. He describes how the autonomic nervous system, HPA axis, and amygdala-based threat circuitry interact with memory and prefrontal narrative systems to create adaptive and maladaptive fear responses. The episode reviews behavioral therapies, drug-assisted psychotherapies, physiological breathing protocols, lifestyle factors, and certain supplements that can help extinguish and replace fearful and traumatic memories.
Host Jay Shetty speaks with physician and researcher Dr. Sara Szal about how hormones function as the body's messaging system, what hormonal imbalance looks like, and why stress and lifestyle are central drivers of issues like fatigue, weight gain, mood changes, and fertility challenges. They discuss cortisol, insulin, sex hormones, thyroid function, the impact of chronic stress and relationships, and practical ways to measure and rebalance hormones through testing, nutrition, sleep, stress management, and more informed choices about birth control. The conversation also covers life-stage hormone shifts, the risks and benefits of the birth control pill versus IUDs, natural family planning, and how integrating spirituality and self-awareness with medical science can prevent burnout and support healing.