by DOAC
Stephen speaks with technology ethicist Tristan Harris about how incentives in the tech industry led from social media harms to a new wave of powerful AI systems, and why current AI development is on a trajectory most people would not choose if they saw it clearly. Tristan explains the race toward artificial general intelligence (AGI), the private beliefs and fears of AI leaders, the likely impacts on jobs, politics, and social fabric, and the emerging risks from AI companions and therapy bots. They conclude by outlining potential governance, design, and civic responses that could steer AI onto a narrower, safer path if enough people act in time.
Nov 27, 2025
Internal medicine physician and insulin-resistance specialist Dr. Annette Bosworth explains why she believes routinely generating ketones is central to preventing and reversing many chronic conditions. She discusses insulin's role in aging and disease, the practical steps of her "keto continuum" approach, measurement of glucose and ketones, and tools like sardine fasts and exogenous ketones to break through insulin resistance. She also shares case studies from her practice, the story of using a ketogenic diet alongside her mother's cancer care, and her own legal and political ordeal that tested her faith and resilience.
Nov 24, 2025
The host and guest discuss the concept of the predictive brain, explaining that the brain is not primarily a reactive organ but a prediction engine that prepares actions and experiences based on past learning. Using concrete examples such as language processing, thirst, coffee habits, exercise, trauma, and phobias, they show how prediction shapes perception, emotion, and bodily regulation. They also explore cultural inheritance, meaning-making, identity, and practical ways to change entrenched patterns by creating new experiences and dosing oneself with prediction error.
Nov 21, 2025
The host interviews Kevin about his journey from an unfocused teenager in North Philadelphia to a globally successful stand-up comic, actor, and entrepreneur. Kevin describes how his strict mother, his father's failures, and his own 'dummy moments' taught him to finish what he starts, persist through a 13-year grind before his big break, and later learn the worlds of business and investing by admitting ignorance and asking questions. They also explore the costs of relentless ambition, his approach to fatherhood and masculinity, setting boundaries to manage stress, and his evolving perspective as reflected in his stand-up special "Acting My Age."
Nov 20, 2025
The conversation explores the components of happiness, distinguishing between pleasure, enjoyment, and satisfaction, and explaining how social connection and struggle contribute to deeper fulfillment. It examines the hedonic treadmill, the arrival fallacy, and an equation for satisfaction that emphasizes managing desires rather than accumulating more. The discussion then shifts to setting better goals around faith, family, friendship, and work that serves others, using fitness and habits as examples, and concludes with a framework for life meaning based on coherence, purpose, and significance, illustrated through two probing questions about why one is alive and what one is willing to die for.
Nov 14, 2025
Tim Ferriss discusses his frameworks for learning quickly, choosing projects, and structuring life around relationships and energy rather than rigid long-term plans. He shares in depth about his history of childhood sexual abuse, severe depression, and near-suicide, and explains how he has used tools like psychedelic-assisted therapy, brain stimulation, and metabolic psychiatry to dramatically improve his mental health. The conversation also explores emerging bioelectric medicine, the importance of social connection, the pitfalls of modern dating, and practical practices like annual mini-retirements to sustain long-term well-being and productivity.
Nov 13, 2025
Steven interviews Natalie, an entrepreneur who has co-founded two nine-figure companies, Cardone Ventures and Tenex Health, and worked directly with over 15,000 business owners to grow and scale their organizations. She explains her frameworks for goal setting, hiring, communication, time management, and sales, and contrasts the mindset and behaviors of the top 1% with those who struggle to build wealth. The conversation also explores hard work versus burnout, respect versus likability, AI-enabled opportunities, the coming women's wealth transfer, and the importance of believing you can learn any skill you need.
Nov 10, 2025
The conversation focuses on the oral microbiome, particularly the role of specific bacteria such as Fusobacterium nucleatum in tumor growth and oral-systemic health links. Victoria explains how habits like sugar consumption, beverage choices, brushing techniques, and smoking affect oral bacteria, saliva, tooth decay, and gum disease. She also discusses safe approaches to teeth whitening, the use of probiotics for oral health, and practical strategies like proper brushing, flossing, and drinking through straws to protect teeth.
Nov 7, 2025
Harvard neuroscientist Dr. Jill Bolte-Taylor explains how four anatomically distinct brain systems shape our thoughts, emotions, and behavior, and argues that we can learn to consciously choose which "character" to lead with in any moment. She recounts her catastrophic left-hemisphere hemorrhagic stroke, eight-year recovery, and how losing her left brain radically shifted her perspective on identity, trauma, and the preciousness of life. Throughout the conversation she connects brain anatomy to practical tools for emotional regulation, trauma integration, lifestyle choices, and cultivating a more balanced, peaceful mind.
Nov 6, 2025
Brene Brown discusses how vulnerability, courage, and emotional "armor" shape our lives, relationships, and leadership. She shares personal stories from a chaotic Texas childhood, her long-term marriage, and caring for her mother with dementia, illustrating how shame, fear, and control patterns develop and how they can be changed. The conversation also explores power and politics, systems thinking, responsibility of large platforms, connection and belonging, and the practical skills needed to build trust, recover from failure, and live more bravely.
Nov 3, 2025
The episode segment critiques the simplistic 'calories in, calories out' model of weight loss by explaining how the body adapts its basal metabolic rate to caloric restriction. The guest emphasizes the central role of hormones-especially insulin-in determining whether the body stores or burns fat, arguing that food is an instruction to the body, not just a source of calories. They discuss intermittent fasting, snacking patterns, exercise, and the concept of breakfast as tools or factors that influence hormonal balance and long-term weight regulation.
Oct 31, 2025
Kamala Harris discusses her upbringing in a civil-rights-oriented family, her legal career, and how those experiences shaped her commitment to justice and public service. She reflects in detail on serving as vice president, the 107‑day presidential campaign, internal tensions within the Biden White House, and her experiences debating Donald Trump. Harris also talks about media dynamics, disinformation, her regrets about not having more time to campaign, the emotional impact of losing the 2024 election, and how she is thinking about a potential future run for president.
Oct 30, 2025
The host and four women's health experts explore how female physiology, hormones, and life stages change the way women should approach exercise, nutrition, fasting, recovery, and sleep. They explain why most fitness and medical research based on men fails women, detail how the menstrual cycle and perimenopause affect training and metabolism, and outline practical protocols for strength training, cardio, bone health, and weight management. The conversation also addresses fertility, energy availability, environmental toxins, supplements, and the need for women to advocate for their own health throughout life.
Oct 27, 2025
The host and an unnamed relationship expert discuss whether traditional institutions like marriage and the nuclear family still make sense in modern society, examining both their social functions and personal trade-offs. They explore what actually predicts satisfaction in long-term partnerships, emphasizing individual well-being, resilience, and open-mindedness over rigid value alignment. The conversation also covers gendered dating preferences, evolutionary versus socialized drivers of attraction, and how self-esteem and societal narratives shape who we choose and how we evaluate potential partners.
Oct 24, 2025
Mentalist Oze Perlman explains that he cannot literally read minds but has spent decades learning to read people through observation, suggestion, and influence. He shares how overcoming fear of rejection, making interactions about others, systematically taking notes, and improving memory have driven his success on stage and in business. The conversation covers practical techniques for persuasion, confidence, goal setting, habit formation, storytelling, and maintaining childlike wonder while navigating ambition, fame, and mortality.
Oct 23, 2025
Jürgen Klopp discusses his upbringing in Germany, the contrasting influences of his caring mother and demanding father, and how those experiences shaped his competitive mindset, work ethic, and confidence. He explains his evolution from an average player and early father working multiple jobs to a successful manager at Mainz, Dortmund, and Liverpool, focusing heavily on individualized leadership, team culture, pressing football, and learning from failure. Klopp also talks about turning down Manchester United, choosing Liverpool, coping with grief and burnout, leaving Liverpool, his current non-coaching role, his faith, and how he thinks about the possibility of one day returning to management.
Oct 20, 2025
The conversation focuses on how everyday household, beauty, and personal care products can expose people to carcinogens and endocrine-disrupting chemicals, and how small, practical changes can significantly reduce that exposure. Dr Yvonne Burkart explains links between environmental chemicals and rising cancer incidence, especially breast cancer, and describes research showing that removing certain ingredients from products lowered breast cancer gene expression in just 28 days. She offers detailed guidance on identifying problematic ingredients like "fragrance" and phthalates in deodorants, candles, and incense, highlights children's particular vulnerability via contaminated household dust, and proposes safer alternatives such as essential-oil-based products and low-emission beeswax candles.
Oct 17, 2025
The host convenes four female health experts from exercise physiology, fertility, OB/GYN menopause care, and orthopedics to discuss women's hormonal health across the lifespan. They cover research bias against women, differences between male and female physiology, menstrual cycles as a vital sign, PCOS and endometriosis, contraception, fertility planning, perimenopause and menopause, and the role of lifestyle and hormone therapy in long-term health. Throughout, they emphasize that missing or irregular periods, chronic inflammation, and insulin resistance are early warning signs and that women can and should advocate for better-informed care.
Oct 16, 2025
Neil deGrasse Tyson discusses mortality, meaning, and the "cosmic perspective," arguing that humans are literally made of stardust and fundamentally connected to the universe and each other. He explores religion and spirituality, the evolution of belief, simulation theory, artificial intelligence, space travel and why Mars colonies are unlikely soon, as well as black holes, alien life, UFO claims, and why astrology and other untested beliefs can be dangerous when they replace objective truth. Throughout, he emphasizes scientific literacy, humility about what we know, and the importance of creating, rather than searching for, meaning in life.
Oct 13, 2025
Peter Attia explains how he structures his weekly training to prioritize longevity, balancing resistance work, zone 2 cardio, and VO2 max training while minimizing injury risk. He details rep ranges for strength, hypertrophy, and endurance, his specific warm-up approach using dynamic neuromuscular stabilization and jumping, and why muscle mass, grip strength, and power are crucial for healthy aging. The conversation also covers glucose metabolism, the dangers of falls in older age, the role of the nervous system in flexibility, and a simple three-day resistance training split.
Oct 10, 2025
Louis Tomlinson discusses his journey from a working-class upbringing in Doncaster to global fame with One Direction, and the impact that sudden success and its end had on his identity and mental health. He opens up in detail about losing his mother and younger sister, how those tragedies reshaped his sense of purpose and responsibility toward his family, and his evolving relationship with former bandmate Liam Payne, including Liam's death. Louis also reflects on fatherhood, redefining success in his solo career, and how his current happiness, relationship, and outlook are shaping his new, more uplifting music.
Oct 9, 2025
Stephen and Morgan Housel discuss why most financial advice focuses on saving and investing while almost nothing is said about how to spend money in a way that actually improves life. Morgan explains the psychology behind spending, status, envy, trauma around money, and argues that true wealth is more about independence and contentment than income or possessions. They also challenge the myth of passive income, explore inequality and social media's impact on expectations, and examine how to minimize future regret through clearer values and better decisions.
Oct 6, 2025
In this replayed conversation, Sadhguru challenges the common notion that humans must discover a singular life purpose, arguing instead that life has no inherent purpose and that inner joy and stability should be the focus. He emphasizes taking responsibility for one's inner experience, learning how the mind and body function, and cultivating inner balance through conscious practices rather than depending on external circumstances. The discussion touches on the impacts of social conditioning, trauma, the limits of intellect, and the importance of turning inward to manage one's own inner state.
Oct 3, 2025
Dr. Robert Lustig explains how dopamine-driven behaviors and ultra-processed food, especially sugar, can create a "hostage brain" by rewiring reward pathways and degrading metabolic and brain health. He details mechanisms linking sugar, artificial sweeteners, mitochondrial dysfunction, and reactive oxygen species to Alzheimer's, cancer, depression, and other chronic diseases, while contrasting environmental versus genetic risk. The conversation also covers GLP-1 weight-loss drugs, vaccines and public health communication, loneliness, serotonin and oxytocin, practical strategies to reduce sugar and ultra-processed food, and emerging research on psychedelics and brain rewiring.
Oct 2, 2025
The host brings together three thinkers-an atheist/agnostic philosopher, a Christian apologist, and a Hindu-trained psychiatrist and spiritual practitioner-to explore why so many people today report a lack of meaning and purpose. They debate whether purpose is objective or purely subjective, how religion, spirituality, neuroscience, trauma, technology, and social conditions contribute to a "meaning crisis," and whether any worldview can adequately address deep suffering such as children dying of cancer. Alongside high-level philosophical disagreement, they also discuss concrete psychological tools and spiritual practices that can help individuals move from feeling lost to experiencing more direction and purpose in their own lives.
Sep 29, 2025
The conversation explores the concept of a "vocal image" and how it shapes the way others form beliefs about us beyond our visual appearance. Vinh Giang walks the host through live exercises on melody, rate of speech, volume, and emotional tonality, using famous movie monologues to demonstrate how vocal variety changes how messages are felt and remembered. They also discuss how facial expressions and nonverbal cues during listening can convey engagement or unintentionally signal impatience.
Sep 26, 2025
Former U.S. Secret Service agent Evy Poumpouras discusses why over-identifying with past trauma and 'authenticity' can disempower people, arguing instead for radical acceptance of reality, emotional self-regulation, and personal responsibility. She explains concepts like cognitive load, decision fatigue, and the 'iceberg' model of personality, and shares lessons from presidents and law enforcement on confidence, communication, and decision-making under pressure. The conversation also explores victim mindsets, boundaries in relationships and work, the dangers of low-vibration environments, and how online culture and algorithms are amplifying polarization and political violence.
Sep 25, 2025
Cardiologist Pradip Jamnadas explains how modern lifestyles drive heart disease through insulin resistance, visceral fat, chronic inflammation, and hidden factors like gut dysfunction, toxins, and mold. He describes how fasting, time‑restricted eating, targeted exercise, and gut repair can reduce visceral fat, lower inflammation, improve vascular health, and rebalance the autonomic nervous system. The conversation also covers LDL particle quality, the limitations and side effects of statins, practical diet guidance, vagus nerve "hacks", and his personal reflections on mortality and living in the present moment.
Sep 22, 2025
The conversation explores how common trauma is, how it affects brain function, and how eye movement desensitization and reprocessing (EMDR) can change traumatic responses. The guest explains specific brain regions involved in danger signaling, body awareness, and time perception, showing how trauma leads to chronic fear, loss of perspective, and reliving rather than remembering events. They then discuss EMDR's mechanisms, research evidence, and demonstrate a brief EMDR-style exercise that quickly reduces the host's emotional activation around a recent unpleasant experience.
Sep 19, 2025